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Karl Fischer Reagent Selection Guide

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VICOMETER — Moisture Analyzer Reagent Selection Guide
VICOMETER
Moisture Analyzer Reagent Selection Guide
Karl Fischer Reagent Selection Guide for VICOMETER Moisture Analyzers
Applicable instruments: WKT-A series (coulometric) · WKT-C series (volumetric)
   Methods covered: volumetric (one-component/two-component) · coulometric (with/without diaphragm)
   First-choice recommended reagents: Tianjin Saifurui SFR · preferred imports: Honeywell HYDRANAL / Merck Aquastar
   Standard reagent shipped with instrument: coulometric KFR-C02 | volumetric KFR-03(Suitable for most industries and samples)
   Applicable industries: pharmaceuticals · chemicals · petroleum · food · electronics · new energy
   Version: V3.0 | Date: August 2026
1

Step 1: Select the Measurement Method

Choose the volumetric or coulometric method based on the estimated moisture content range of the sample. This is the first step in selection and determines the subsequent reagent type.

volumetric Volumetric

Applicable Moisture Content:0.1% ~ 100%
     Instrument ModelWKT-C Series
     Principle:The titrant is precisely dosed through a burette, and the moisture content is calculated from the volume consumed
     Features:Wide application range, simple operation, low reagent cost

→

coulometric Coulometric

Applicable Moisture Content:1ppm ~ 1%(<1%)
     Instrument ModelWKT-A Series
     Principle:Iodine is generated in situ by electrolysis, and the moisture content is calculated from the electrolysis charge
     Features:Extremely high sensitivity, no titer calibration required, ideal for trace moisture

Quick Check:If the sample moisture content is > 0.1% (e.g., more than 100mg of water), choose the volumetric method; if the moisture content is < 0.1% (e.g., ppm level), choose the coulometric method. When in doubt, a preliminary test is recommended before deciding.
2

Step 2: Volumetric Reagent Selection (WKT-C Series)

Volumetric reagents are divided into one-component and two-component systems.The first choice is the Tianjin Saifurui SFR series reagents; for imported reagents, Honeywell HYDRANAL and Merck Aquastar are preferred.
★ VICOMETER Standard Reagent Shipped with Instrument (Volumetric)

   KFR-03(Pyridine-free · one-component · titer ~3 mg/mL) — the standard reagent shipped free with VicoMeter WKT-C series volumetric moisture analyzers.
   Wide Application Range: Covers the 0.5%~10% moisture range and is suitable for routine sample testing in most industries such as pharmaceuticals, chemicals, petroleum and food.
   Ready to Use Out of the Box: Start testing without additional purchases — the first-choice general reagent for daily testing.
Reagent Recommendation Priority:    First choice: Saifurui SFR     Preferred imports: Honeywell HYDRANAL / Merck Aquastar     Others: Sinopharm Hushi / Mitsubishi AQUAMICRON

2.1 One-Component Reagents (Composite / Single Bottle)

TiterApplicable Moisture ContentSample TypeFirst choice: Saifurui SFRPreferred imports: Honeywell / MerckSelection Tag
~0.5 mg/mL0.01% ~ 0.5%Extremely low moisture: dry solids, pure solventsKFR-15 (pyridine-free)Hydranal Composite 1(34827)
Aquastar CombiTitrant 1(1.88001)
volumetric
~1 mg/mL0.01% ~ 1%Low moisture: dry solids, organic solventsKFR-1 (pyridine-free)Hydranal Composite 1(34827)
Aquastar CombiTitrant 1(1.88001)
volumetric
~2 mg/mL0.1% ~ 5%Medium moisture: chemicals, APIsKFR-2 (pyridine-free)Hydranal Composite 2(34806)
Aquastar CombiTitrant 2(1.88002)
volumetric
~3 mg/mL0.5% ~ 10%Medium-to-high moisture: general chemicalsKFR-03(pyridine-free)Standard with instrument
KFR-06 (methanol type)
Hydranal Composite 2(34806)
Aquastar CombiTitrant 2(1.88002)
VICOMETER standard
~5 mg/mL1% ~ 100%High moisture: food, aqueous solutions, slurriesKFR-05 (pyridine-free)Hydranal Composite 5(34805)
Aquastar CombiTitrant 5(1.88005)
volumetric
~3 mg/mL (with pyridine)0.5% ~ 10%Traditional formula, high reactivityKFR-08 (with pyridine)—With pyridine
~5 mg/mL (with pyridine)1% ~ 100%Traditional formula, high reactivityKFR-09 (with pyridine)—With pyridine
~5 mg/mLAldehyde and ketone samplesCompounds containing aldehyde/ketone groups (side reactions with methanol)KFR-04 (pyridine-free, for aldehydes and ketones)Hydranal Composite 5K(34816)
Aquastar CombiTitrant 5 Keto(1.88006)
For aldehydes and ketones

2.2 Two-Component Reagents (Titrant + Solvent)

TitrantTiterMatching SolventFirst choice: Saifurui SFRPreferred imports: Honeywell / MerckSelection Tag
Titrant 2~2 mg/mLGeneral solventKFR-T1 / KFR-T2 (pyridine-free)Hydranal Titrant 2(34811)+ Solvent(34800)
Aquastar Titrant 2(1.88011)+ Solvent(1.88015)
volumetric
Titrant 3~3 mg/mLGeneral solventKFR-T03 / KFR-T06 (pyridine-free)Hydranal Titrant 2(34811)+ Solvent(34800)volumetric
Titrant 5~5 mg/mLGeneral solventKFR-T02 / KFR-T05 (pyridine-free)Hydranal Titrant 5(34801)+ Solvent(34800)
Aquastar Titrant 5(1.88010)+ Solvent(1.88015)
volumetric
Titrant 3/5 (with pyridine)3 / 5 mg/mLGeneral solventKFR-T08 / KFR-T09 (with pyridine)—With pyridine
Titrant 5 E~5 mg/mLSolvent E (ethanol type)—Hydranal Titrant 5 E(34712)+ Solvent E
(low-toxicity ethanol type)
Low toxicity recommended
——Oil-specific solventKFR-T02A / KFR-T03A solventHydranal Solvent Oil(34749)/ Solvent CMOil-specific
One-Component vs Two-Component: How to Choose?
   One-component:One bottle serves as both titrant and solvent — simple to operate, suitable for routine rapid testing with small sample volumes
   Two-component:Titrant and solvent are separate — higher titration efficiency, more stable titer and longer shelf life, suitable for large sample batches or high-precision requirements
3

Step 3: Coulometric Reagent Selection (WKT-A Series)

Coulometric reagents are selected based on the electrolytic cell type (with/without diaphragm) and sample type. The WKT-A series coulometric moisture analyzers support both diaphragm and diaphragm-free electrolytic cells.The first choice is the Saifurui SFR coulometric series reagents; for imports, Honeywell and Merck are preferred.
★ VICOMETER Standard Reagent Shipped with Instrument (Coulometric)

   KFR-C02(Pyridine-free · universal anode/cathode · 1.5gH₂O/100mL) — the standard reagent shipped free with VicoMeter WKT-A series coulometric moisture analyzers.
   Extremely Wide Application Range: Universal for diaphragm cells, covering routine sample testing in most industries such as pharmaceuticals, chemicals, petroleum, food and electronics.
   Also Suitable for Karl Fischer Ovens: Used with a Karl Fischer oven, it can measure the moisture of insoluble samples such as solids and plastics.
   Ready to Use Out of the Box: Start testing without additional purchases — the first-choice general reagent for trace moisture analysis.

3.1 Diaphragm Electrolytic Cell (WKT-A Series with Diaphragm)

A diaphragm electrolytic cell requires separateAnolyteandCatholyte; the diaphragm separates the anode and cathode compartments, making it suitable for trace moisture determination with higher accuracy requirements.
Reagent TypeFirst choice: Saifurui SFRPreferred imports: Honeywell / MerckApplicable Samples
Anolyte (general)KFR-C02(pyridine-free, 1.5g/100ml)Standard with instrument
KFR-C06 (pyridine-free, 1.5g/100ml)
KFR-C03 (pyridine-free, 1.5g/100ml)
Hydranal Coulomat A(34807)
Aquastar CombiCoulomat(1.09255)
AQUAMICRON AX(604-07485)/ AXI(621-01755)
Organic solvents, inorganic substances, gases; suitable for most industries
Catholyte (general)KFR-C06 Catholyte
(5mL×10 vials/box)
Hydranal Coulomat CG(34840)
AQUAMICRON CXU(602-07501)
For use with general anolyte
Anolyte (for aldehydes and ketones)KFR-C04 (pyridine-free, 1.0g/100ml)
KFR-C12 (alcohol-ether type, 1.0g/100ml)
KFR-C18 (alcohol-free, chloroform-free, for aldehydes and ketones)
Hydranal Coulomat AK(34820)
Aquastar Anolyte K(1.09255)
AQUAMICRON AKX(605-07591)
Ketones, aldehydes, silicone oils, lower carboxylic acids
Catholyte (for aldehydes and ketones)KFR-C04 Catholyte
(5mL×10 vials/box)
Hydranal Coulomat CG-K(34821)
Aquastar Catholyte K
For use with aldehyde/ketone anolyte
For lithium batteries/electrolytesKFR-C07 (pyridine-free, 1.2g/100ml)
KFR-C09 (with pyridine, 1.0g/100ml)
KFR-C10 (for boron salts)
KFR-C11 (for additives)
KFR-C16 (diol type)
Hydranal Coulomat E(34808)/ ADG(34809)
HYDRANAL NEXTGEN A-FA + C-FA
Lithium battery electrolytes, VC, FEC, lithium salts, additives
Universal anode/cathode typeKFR-C01 (with pyridine, 1.0g/100ml)
KFR-C08 (pyridine-free, 1.2g/100ml, universal with/without diaphragm)
Hydranal Coulomat A(34807)+ CG(34840)
(mixed anode/catholyte type)
General samples, replacing imported reagents

3.2 Diaphragm-Free Electrolytic Cell (WKT-A Series Diaphragm-Free)

A diaphragm-free electrolytic cell requires onlyone electrolyte— simpler to operate with no catholyte replacement, ideal for routine high-frequency testing.
Reagent TypeFirst choice: Saifurui SFRPreferred imports: Honeywell / MerckRemarks
General electrolyte (single solution)KFR-C03 (pyridine-free, 1.5g/100ml, chlorinated-hydrocarbon-free)
KFR-C08 (pyridine-free, 1.2g/100ml, universal with/without diaphragm)
KFR-C20 (pyridine-free, same as 34836, universal anode/cathode)
Hydranal Coulomat AG(34836)
Aquastar CombiCoulomat Fritless(1.09257)
AQUAMICRON FLS(632-07065)
One reagent is enough; no catholyte needed
For Karl Fischer ovensKFR-C02Standard with instrument · suitable for Karl Fischer ovens
KFR-C19 (carbonate/glycolamine type, extremely low volatility)
—KFR-C02 general type is also suitable for Karl Fischer ovens; routine solid samples can directly use the standard reagent; KFR-C19 is the extremely-low-volatility type, ideal for scenarios with extremely strict drift requirements
With vs Without Diaphragm: How to Choose?
   With diaphragm:Higher accuracy and less interference, suitable for demanding QC and R&D scenarios
   Without diaphragm:Simple operation and low maintenance cost, suitable for rapid screening of large numbers of routine samples
   VICOMETER recommends diaphragm electrolytic cells for trace moisture analysis (<100ppm).
4

Complete Model Catalog of Tianjin Saifurui SFR Reagents

The following is a complete list of Karl Fischer reagent models from Tianjin Saifurui Technology Co., Ltd. (brand SFR) — the first-choice recommended reagents for VICOMETER moisture analyzers.
Saifurui SFR Advantages:Three independent production lines (pyridine-free volumetric / pyridine-containing volumetric / coulometric) to avoid cross-contamination; annual output of 600,000 liters with a full range (volumetric, coulometric, aldehyde/ketone-specific); flexible packaging, high quality at low prices, replacing imported reagents. Compatible with Mettler, Metrohm, KCM, Mitsubishi and domestic moisture analyzers.

4.1 Volumetric — One-Component Reagents

ModelTypeTiter FPackage SizeApplication Notes
KFR-15Pyridine-free&ge;0.5 mgH₂O/mL500mL / 1LLow titer, for samples with extremely low moisture
KFR-1Pyridine-free&ge;1 mgH₂O/mL500mL / 1LLow-moisture samples, dry solids, pure solvents
KFR-2Pyridine-free&ge;2 mgH₂O/mL500mL / 1LMedium moisture, chemicals, APIs
KFR-03Standard with instrumentPyridine-free&ge;3 mgH₂O/mL500mL / 1LMedium-to-high moisture, general chemicals.VICOMETER WKT-C series factory standard, suitable for routine samples in most industries
KFR-05Pyridine-free&ge;5 mgH₂O/mL500mL / 1LHigh moisture, food, aqueous solutions, slurries
KFR-06Methanol type&ge;3 mgH₂O/mL500mL / 1LMethanol system, suitable for general samples
KFR-08With pyridine&ge;3 mgH₂O/mL500mL / 1LTraditional pyridine-containing formula, high reactivity
KFR-09With pyridine&ge;5 mgH₂O/mL500mL / 1LTraditional pyridine-containing formula, high-moisture samples
KFR-04Pyridine-free · for aldehydes and ketones&ge;5 mgH₂O/mL500mL / 1LFor aldehyde and ketone samples, avoiding acetalization reactions
KFR-10With pyridine · for aldehydes and ketones&ge;3 mgH₂O/mL500mL / 1LWith pyridine, for aldehydes and ketones

4.2 Volumetric — Two-Component Reagents (A: Solvent + B: Titrant)

ModelTypeTiter FPackage SizeApplication Notes
KFR-T1Pyridine-free&ge;1 mgH₂O/mLA:500mL/1L B:500mL/1LLow-moisture two-component
KFR-T2Pyridine-free&ge;2 mgH₂O/mLA:500mL/1L B:500mL/1LMedium-moisture two-component
KFR-T03Pyridine-free&ge;3 mgH₂O/mLA:500mL/1L B:500mL/1LMedium-to-high-moisture two-component
KFR-T06Pyridine-free&ge;3 mgH₂O/mLA:500mL/1L B:500mL/1LMedium-to-high-moisture two-component
KFR-T02Pyridine-free&ge;5 mgH₂O/mLA:500mL/1L B:500mL/1LHigh-moisture two-component
KFR-T05Pyridine-free&ge;5 mgH₂O/mLA:500mL/1L B:500mL/1LHigh-moisture two-component
KFR-T08With pyridine&ge;3 mgH₂O/mLA:500mL/1L B:500mL/1LPyridine-containing two-component
KFR-T09With pyridine&ge;5 mgH₂O/mLA:500mL/1L B:500mL/1LPyridine-containing two-component (high titer)
KFR-T04A/T04BPyridine-free · for aldehydes and ketones1~5 mgH₂O/mL500mL / 1LAldehyde/ketone-specific solvent + titrant combination
KFR-T02A / KFR-T03APyridine-free · solvent—500mL / 1LRoutine volumetric solvent, used with titrant
KFR-12 / KFR-13Solutions A and B3~5 mgH₂O/mLA: 500mL/1L B: 500mL/1LSolution A is an iodine-methanol solution (titrant); Solution B is a sulfur dioxide-methanol solution (solvent)

4.3 Coulometric Reagents

ModelTypeNominal Moisture ContentPackage SizeElectrolytic Cell/Application
KFR-C01With pyridine · universal anode/cathode1.0 gH₂O/100mL500mL / 250mLUniversal for diaphragm cells; requires water equilibration before first use
KFR-C02Standard with instrumentPyridine-free · universal anode/cathode1.5 gH₂O/100mL500mLUniversal for diaphragm cells.VICOMETER WKT-A series factory standard, suitable for most industries and samples, and also for Karl Fischer ovens
KFR-C03Pyridine-free · chlorinated-hydrocarbon-free1.5 gH₂O/100mL500mLUniversal with/without diaphragm, eco-friendly and chlorine-free
KFR-C04Pyridine-free · for aldehydes and ketones1.0 gH₂O/100mLAnolyte: 500mL Catholyte: 5mL×10 vialsMeasures aldehydes and ketones with diaphragm; use with matching catholyte
KFR-C06Pyridine-free · with diaphragm1.5 gH₂O/100mLAnolyte: 500mL Catholyte: 5mL×10 vialsUniversal for diaphragm cells; use with matching catholyte
KFR-C07Pyridine-free · for lithium batteries1.2 gH₂O/100mL500mLTesting of lithium battery additives and electrolytes; no water equilibration required
KFR-C08Pyridine-free · universal with/without diaphragm1.2 gH₂O/100mLAnolyte: 500mL Catholyte: 5mL×10 vialsReplaces imported reagents; quickly reaches stable drift on first use
KFR-C09With pyridine · electrolyte-specific1.0 gH₂O/100mL500mLTesting of electrolytes containing VC, FEC, lithium salts, etc.; fast reaction and long life
KFR-C10Pyridine-free · for boron salts1.0 gH₂O/100mL500mLTesting of pure LiBOB, ODFB and other boron salts; universal anode/cathode with diaphragm
KFR-C11Pyridine-free · for additives1.0 gH₂O/100mL500mLTesting of VC, FEC, DTD and other additives; universal anode/cathode with diaphragm
KFR-C12Alcohol-ether type1.0 gH₂O/100mL500mLMinimal side reactions with aldehyde/ketone samples; suitable for VC/FEC/NMP/acetone, etc.
KFR-C16Diol · diaphragm-specific—500mLLithium salts/FEC/VC-containing electrolytes; good solubility, no crystallization
KFR-C18Alcohol-free, chloroform-free · for aldehydes and ketones1.0 gH₂O/100mL500mLVC/FEC/NMP/acetone/cyclohexanone/vinyl ethers; minimal side reactions
KFR-C19Carbonate/glycolamine · for Karl Fischer ovens—500mLFor Karl Fischer ovens; extremely low volatility, stable drift, universal with/without diaphragm
KFR-C20Pyridine-free · universal anode/cathode1.5 gH₂O/100mL500mLReplaces imported reagents (same as 34836); universal with/without diaphragm and for anolyte/catholyte

4.4 Water Standards

ModelNominal Moisture Content ValuePackage SizeApplication
KFR-W010.1 mg/g(0.01%)5mL×10 vialsCoulometric accuracy verification
KFR-W021.0 mg/g(0.1%)5mL×10 vialsCoulometric accuracy verification
KFR-W0310.0 mg/g(1.0%)5mL×10 vialsVolumetric titer calibration
5

Cross-Reference Table of Saifurui Models and Other Brand Reagents

The table below lists the corresponding models of imported brands (Honeywell HYDRANAL, Merck Aquastar, Mitsubishi AQUAMICRON) and the domestic brand (Sinopharm Hushi) that each Saifurui SFR reagent can replace, making it easy for customers to choose flexibly according to their purchasing channels.
Replacement Principle:Reagents with the same titer and type (one-component/two-component, with/without diaphragm, general/aldehyde-ketone-specific) are in principle interchangeable. When changing brands, calibration verification is recommended first; confirm result consistency before batch use.

5.1 Volumetric One-Component Reagent Comparison

Saifurui SFR
(part number = model)
Titer / TypeHoneywell HYDRANAL
(order no.)
Merck Aquastar
(product no.)
Mitsubishi AQUAMICRON
(part no.)
Sinopharm Hushi
(part number = model)
KFR-150.5 / pyridine-freeComposite 1
Part No.: 34827
CombiTitrant 1
No.: 1.88001
SS-Z 1mg
Part No.: 631-03495
—
KFR-11 / pyridine-freeComposite 1
Part No.: 34827
CombiTitrant 1
No.: 1.88001
SS-Z 1mg
Part No.: 631-03495
KFR-1 Pyridine-Free
KFR-22 / pyridine-freeComposite 2
Part No.: 34806
CombiTitrant 2
No.: 1.88002
SS-Z 3mg
Part No.: 634-03505
KFR-2 Pyridine-Free
KFR-03Standard with instrument3 / pyridine-freeComposite 2
Part No.: 34806
CombiTitrant 2
No.: 1.88002
SS-Z 3mg
Part No.: 634-03505
KFR-3 Pyridine-Free
KFR-055 / pyridine-freeComposite 5
Part No.: 34805
CombiTitrant 5
No.: 1.88005
SS-Z 5mg
Part No.: 631-03515
KFR-5 Pyridine-Free
KFR-063 / methanol typeComposite 2
Part No.: 34806
CombiTitrant 2
No.: 1.88002
—KFR-3 Methanol Type
KFR-083 / with pyridineComposite 2 (with pyridine)—SS 3mg (with pyridine)
Part No.: 601-07015
KFR-8 With Pyridine
KFR-095 / with pyridineComposite 5 (with pyridine)—SS 10mg (with pyridine)
Part No.: 603-07215
KFR-9 With Pyridine
KFR-045 / for aldehydes and ketonesComposite 5K
Part No.: 34816
CombiTitrant 5 Keto
No.: 1.88006
SS-Z 5mg + KTX
Part No.: 631-03515 / 632-03545
For aldehydes and ketones

5.2 Volumetric Two-Component Reagent Comparison

Saifurui SFR
(part number = model)
Titer / TypeHoneywell HYDRANAL
(order no.)
Merck Aquastar
(product no.)
Mitsubishi AQUAMICRON
(part no.)
KFR-T11 / pyridine-free—Titrant 1 + Solvent—
KFR-T22 / pyridine-freeTitrant 2 + Solvent
Part No.: 34811 + 34800
Titrant 2 + Solvent
No.: 1.88011 + 1.88015
SS-Z 3mg + GEX
Part No.: 634-03505 + 608-07525
KFR-T03 / T063 / pyridine-freeTitrant 2 + Solvent
Part No.: 34811 + 34800
Titrant 2 + Solvent
No.: 1.88011 + 1.88015
SS-Z 3mg + GEX
Part No.: 634-03505 + 608-07525
KFR-T02 / T055 / pyridine-freeTitrant 5 + Solvent
Part No.: 34801 + 34800
Titrant 5 + Solvent
No.: 1.88010 + 1.88015
SS-Z 5mg + GEX
Part No.: 631-03515 + 608-07525
KFR-T083 / with pyridine———
KFR-T095 / with pyridine———
KFR-T04A/T04BTwo-component for aldehydes and ketonesTitrant 5 + Solvent K
Part No.: 34801 + 34738
Titrant 5 + Solvent Keto
No.: 1.88010 + 1.88007
SS-Z 5mg + KTX
Part No.: 631-03515 + 632-03545
KFR-T02A / T03AGeneral solventSolvent / Solvent Oil
Part No.: 34800 / 34749
Solvent / Solvent Oil
No.: 1.88015 / 1.88020
GEX / OLX
Part No.: 608-07525 / 635-03535

5.3 Coulometric Reagent Comparison

Saifurui SFR
(part number = model)
Type / ApplicationHoneywell HYDRANAL
(order no.)
Merck Aquastar
(product no.)
Mitsubishi AQUAMICRON
(part no.)
Sinopharm Hushi
(part number = model)
KFR-C01With pyridine · universal for diaphragm cellsCoulomat A + CG
Part No.: 34807 + 34840
CombiCoulomat frit
No.: 1.09255
AX + CXU
Part No.: 604-07485 + 602-07501
Pyridine-containing coulometric electrolyte
KFR-C02Standard with instrument
KFR-C03
Pyridine-free · universal with/without diaphragmCoulomat A / AG
Part No.: 34807 / 34836
CombiCoulomat frit / Fritless
No.: 1.09255 / 1.09257
AXI / FLS
Part No.: 621-01755 / 632-07065
Pyridine-free coulometric electrolyte
KFR-C06Pyridine-free · universal for diaphragm cellsCoulomat A (anolyte)
Part No.: 34807
Coulomat CG (catholyte)
Part No.: 34840
CombiCoulomat frit
No.: 1.09255
AX (anolyte)
Part No.: 604-07485
CXU (catholyte)
Part No.: 602-07501
Pyridine-free anolyte/catholyte
KFR-C04Pyridine-free · for aldehydes and ketonesCoulomat AK + CG-K
Part No.: 34820 + 34821
CombiCoulomat frit
(for aldehydes and ketones) No.: 1.09255
AKX + CXU
Part No.: 605-07591 + 602-07501
Electrolyte for aldehydes and ketones
KFR-C08Pyridine-free · universal with/without diaphragmCoulomat AG
Part No.: 34836
CombiCoulomat Fritless
No.: 1.09257
FLS
Part No.: 632-07065
Diaphragm-free electrolyte
KFR-C20Pyridine-Free · Universal for Anode & Cathode (Same as 34836)Coulomat AG
Part No.: 34836
CombiCoulomat Fritless
No.: 1.09257
FLS
Part No.: 632-07065
Universal Electrolyte
KFR-C07For lithium batteries/electrolytesCoulomat E / ADG
Cat. No.: 34808 / 34809
———
KFR-C09With pyridine · electrolyte-specificNEXTGEN Coulomat A-FA———
KFR-C12For Alcohols/Ethers · Aldehydes & KetonesCoulomat AK
Cat. No.: 34820
CombiCoulomat frit
No.: 1.09255
AKX
Cat. No.: 605-07591
—
KFR-C18Alcohol-free, chloroform-free · for aldehydes and ketonesCoulomat AK
Cat. No.: 34820
———
KFR-C16Diols · Lithium Battery (With Diaphragm)Coulomat ADG
Cat. No.: 34809
———
KFR-C19For Karl Fischer ovens————

5.4 Comparison of Water Standards

Saifurui SFR
(part number = model)
Nominal Moisture Content ValueHoneywell HYDRANAL
(order no.)
Merck Aquastar
(product no.)
Mitsubishi AQUAMICRON
(part no.)
Application
KFR-W010.1 mg/g(0.01%)Water Std 0.1
Cat. No.: 34847
Water Std 0.01%
Article No.: 1.88050
Water Std 0.1mg
Cat. No.: 639-15101
Coulometric Verification
KFR-W021.0 mg/g(0.1%)Water Std 1.0
Cat. No.: 34828
Water Std 0.1%
Article No.: 1.88051
Water Std 1mg
Cat. No.: 601-07571
Coulometric Verification
KFR-W0310.0 mg/g(1.0%)Water Std 10.0
Cat. No.: 34850
Water Std 1.0%
Article No.: 1.88052
Water Std 10mg
Cat. No.: 608-07581
Volumetric Titer Standardization
6

Step 6: Quick Selection by Industry/Sample Type

Quickly match the recommended method and Saifurui/imported reagent combination based on your actual sample type.

Pharmaceuticals / APIs

Tablets, capsules, APIs, excipients

Standard: KFR-C02(coulometric)
Standard: KFR-03(volumetric)
Imported: Coulomat A (34807) / Composite 2 (34806)

Chemicals / Organic Solvents

Alcohols, esters, ethers, amines

Standard: KFR-C02(coulometric)
Standard: KFR-03(volumetric)
Imported: Coulomat AG (34836) / Composite 2 (34806)

Petroleum / Oils

Gasoline, diesel, lubricating oil, insulating oil

Standard: KFR-C02(coulometric)
Standard: KFR-03 + KFR-T02A Solvent
Imported: Coulomat A (34807) / Solvent Oil (34749)

Food / Beverages

Oils & fats, milk powder, seasonings, alcoholic drinks

Standard: KFR-C02(coulometric)
Standard: KFR-03(volumetric)
Imported: Coulomat A (34807) / Composite 2 (34806)

Aldehydes & Ketones

Acetone, formaldehyde, acetaldehyde, etc.

Dedicated: KFR-04 (Volumetric)
KFR-C04/C12(coulometric)
Imported: Composite 5K (34816) / Coulomat AK (34820)

Electronics / Semiconductors

Electronic-grade solvents, photoresists

Standard: KFR-C02(coulometric)
ppm-Level Accuracy
Imported: Coulomat AG (34836)

New Energy / Lithium Batteries

Electrolytes, cathode & anode materials

Dedicated: KFR-C07/C09 (Coulometric)
Dedicated for Lithium Battery Electrolytes
Imported: NEXTGEN A-FA / Coulomat E (34808)

Gas Analysis

Natural gas, LPG, inert gases

Standard: KFR-C02(coulometric)
+ Gas Sampling Unit
Imported: Coulomat A (34807)

Plastics / Polymers

Pellets, resins, films

Standard: KFR-C02(Coulometric + Karl Fischer Oven)
Standard: KFR-03(Volumetric + Karl Fischer Oven)
Imported: Coulomat A (34807) / Composite 2 (34806)
7

Step 7: Reagent Brand Compatibility Reference

VICOMETER WKT series moisture analyzers are compatible with mainstream Karl Fischer reagent brands. Saifurui SFR is our first choice; for imported reagents, Honeywell HYDRANAL and Merck Aquastar are recommended.
BrandSeriesOriginRecommended Volumetric ModelsRecommended Coulometric ModelsPositioning
Tianjin Saifurui SFRSFR / SaifuruiTianjin, ChinaKFR-03Standard / KFR-02/05 (Pyridine-Free)
KFR-08/09 (With Pyridine)
KFR-04 (For Aldehydes & Ketones)
KFR-T Series (Two-Component)
KFR-C02Standard / C03/C06/C08
KFR-C04 (Aldehydes & Ketones)
KFR-C07/C09 (Lithium Batteries)
KFR-C12/C18 (Aldehydes, Ketones, Alcohols & Ethers)
KFR-C20 (Universal Import Substitute)
First Choice
HoneywellHYDRANAL&reg;GermanyComposite 1/2/5/5K
Cat. No.: 34827/34806/34805/34816
Titrant 2/5 + Solvent
Cat. No.: 34811/34801 + 34800
Coulomat A/AG/CG/AK
Cat. No.: 34807/34836/34840/34820
NEXTGEN A-FA/C-FA
Preferred Import
MerckAquastar&reg;GermanyCombiTitrant 1/2/5/5K
Article No.: 1.88001/1.88002/1.88005/1.88006
Titrant 2/5 + Solvent
Article No.: 1.88011/1.88010 + 1.88015
CombiCoulomat frit (With Diaphragm)
No.: 1.09255
CombiCoulomat Fritless (Without Diaphragm)
No.: 1.09257
Preferred Import
Mitsubishi ChemicalAQUAMICRON&reg;JapanSS-Z 1mg/3mg/5mg
Cat. No.: 631-03495/634-03505/631-03515
GEX/OLX/KTX/SU Solvents
Cat. No.: 608-07525/635-03535/632-03545/603-07335
AX(604-07485)/AXI(621-01755)
AS(601-07255)/AKX(605-07591)
CXU(602-07501)/FLS(632-07065)
Premium Import
Sinopharm HushiSinopharmChinaWith/Without Pyridine Types
For aldehydes and ketones
Electrolytes With/Without PyridineDomestic Option
Aladdin / MacklinAladdin / MacklinChinaPyridine-Free Volumetric Reagents—Domestic Option
Safety Upgrade Recommendation:Honeywell HYDRANAL NEXTGEN series contains no imidazole or other CMR (carcinogenic, mutagenic, reprotoxic) substances, making it a safe alternative to traditional reagents. It is a direct drop-in replacement requiring no change to titration methods. Pharmaceutical and electronics customers with safety requirements are advised to choose it first.
8

Water Standards & Standardization

Whether using volumetric or coulometric methods, regular standardization and verification with water standards is essential to ensure accurate results.
Water Standard TypeNominal Moisture Content ValueApplicable MethodApplicationFirst Choice: SaifuruiPreferred Import
Liquid Water Standard 0.01%0.1 mg/gcoulometricCoulometric accuracy verificationKFR-W01Hydranal Water Std 0.1
Cat. No.: 34847
Aquastar Article No.: 1.88050
Liquid Water Standard 0.1%1.0 mg/gcoulometricCoulometric accuracy verificationKFR-W02Hydranal Water Std 1.0
Cat. No.: 34828
Aquastar Article No.: 1.88051
Liquid Water Standard 1.0%10.0 mg/gvolumetricVolumetric titer calibrationKFR-W03Hydranal Water Std 10.0
Cat. No.: 34850
Aquastar Article No.: 1.88052
Solid Water Standard 1%1.0%Volumetric / Karl Fischer OvenKarl Fischer Oven Verification—Hydranal Water Std KF-Oven
Cat. No.: 34748
Aquastar Article No.: 1.88054
Recommended Standardization Frequency:
   - Re-standardize whenever a new reagent batch is used (volumetric)
   - Verify instrument status with a water standard before first use each day
   - During continuous high-volume testing, verify every 8 hours
   - Although coulometric titration requires no titer standardization, accuracy should still be verified regularly with water standards
9

FAQ & Precautions

Issue/ScenarioCause AnalysisSolutions
High results for aldehyde/ketone samplesAldehydes/ketones undergo acetalization with methanol, generating water and causing positive biasUse aldehyde/ketone-specific reagents: Saifurui KFR-04 / KFR-C04 / KFR-C12; imported Hydranal Composite 5K / Coulomat AK
Poor dissolution of oil samplesOils have low solubility in methanol, forming two phasesUse oil-specific solvents: Saifurui KFR-T02A/T03A; imported Solvent Oil / OLX, or add chloroform as a co-solvent
Strong acid/base samples out of pH rangeOptimal pH for Karl Fischer reaction is 5-7; outside this range the reaction slows or becomes incompleteAdd buffer to adjust pH, or dilute before measurement
Large endpoint drift in coulometric titrationAged electrolyte, contaminated diaphragm, ambient moisture ingressReplace the electrolyte; check seals; keep the environment dry (recommended humidity <60%)
Unstable volumetric titerReagent moisture absorption, improper storage, leaks in the burette systemStore reagents tightly sealed and avoid frequent opening; check burette joint seals; standardize regularly
Solid samples cannot be measured directlySample insoluble in reagent; water cannot be releasedUse a Karl Fischer oven: heat the sample to release water, which is carried into the titration cell by a carrier gas.The standard KFR-C02 universal electrolyte is also suitable for Karl Fischer ovens; conventional solid samples can be used directly. For extremely low volatility requirements, choose Saifurui KFR-C19 oven-dedicated electrolyte
Abnormal results for lithium battery electrolytesVC, FEC, lithium salts and other components react side-wise with methanolUse Saifurui KFR-C07/C09/C10/C11 lithium battery electrolytes; NEXTGEN A-FA is the imported option
Reagent color darkensIodine has been oxidized and released; the reagent may have expiredReplace the reagent immediately; check storage conditions (protect from light, keep cool and sealed)
General Reagent Storage Principles:
   - Storage temperature: 2~8°C in a cool place (some can be stored at room temperature; see the instructions)
   - Protect from light; avoid direct sunlight
   - Use promptly after opening; volumetric reagents should be used within 1 month of opening
   - Coulometric electrolytes should be used within 3 months of opening
   - Pyridine-containing reagents must be managed as hazardous materials; ensure ventilation and protection
   - Shelf life: Saifurui reagents have a 12-month shelf life (sealed in original packaging)
10

Selection Decision Flow Summary

One-page quick decision: the complete path from sample to reagent.
Step 1: Water ContentStep 2: Sample TypeStep 3: Cell TypeStep 4: First Choice SaifuruiStep 4: Preferred Import
> 0.1%
volumetric
WKT-C Series
General Samples—KFR-03Standard
KFR-05 (High Water Content)
KFR-T05 + T02A (Two-Component)
Composite 2(34806)/ Titrant 5(34801)+ Solvent(34800)
Aldehydes & Ketones—KFR-04 (One-Component)
KFR-T04A + T04B (Two-Component)
Composite 5K(34816)/ Titrant 5(34801)+ Solvent K(34738)
Oils—KFR-T05 + KFR-T02A SolventTitrant 5(34801)+ Solvent Oil(34749)
< 0.1%
coulometric
WKT-A Series
General SamplesWith DiaphragmKFR-C02Standard
KFR-C06 (Anolyte) + Catholyte
Coulomat A(34807)+ CG(34840)
General SamplesWithout DiaphragmKFR-C08 / KFR-C20Coulomat AG(34836)
Solids/Plastics
(Karl Fischer Oven)
With/Without DiaphragmKFR-C02Standard · Suitable for Karl Fischer Oven
KFR-C19 (For Extremely Low Volatility)
Coulomat A(34807)
Aldehydes & KetonesWith DiaphragmKFR-C04 (Anolyte)
+ KFR-C04 Catholyte
Coulomat AK(34820)+ CG-K(34821)
Lithium Batteries/ElectrolytesWith DiaphragmKFR-C07 / KFR-C09NEXTGEN Coulomat A-FA + C-FA
Selection Tip:VICOMETER WKT series moisture analyzers ship with standard reagents — coulometric KFR-C02、volumetric KFR-03, suitable for most industries and general samples — ready to use out of the box. The standard KFR-C02 is also suitable for Karl Fischer ovens. If you have any questions about reagent selection, please call the VICOMETER technical hotline; we will provide professional selection advice based on your specific samples and instrument model.

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